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課程名稱 |
分子遺傳學
Molecular Genetics |
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開課學期 |
100-2 |
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授課對象 |
生物資源暨農學院 農藝學系 |
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授課教師 |
林彥蓉 |
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課號 |
Agron5075 |
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課程識別碼 |
621 U5300 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期一5,6,7(12:20~15:10) |
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上課地點 |
農藝112 |
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備註 |
第二,三群選擇必修。與張俊哲合開
總人數上限：48人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1002mol_genet |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
Molecular Genetics is the modern form of Genetics that studies the structure and function of genes at a molecular level. This field includes how genetic information is organized, replicated, expressed, regulated, and transferred from generation to generation. Topics of this course cover important issues from genes to genome and from proteins to proteome (details please see contents in the Syllabus). Concepts and applications of genome analysis and systems biology are also included. |
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課程目標 |
1. The Structure of DNA, and Genome Organization
2. Maintance of the Genome
3. Expression and regulation of Genes
4. Tools in Molecular Genetics
5. Integration of Molecular Genetics in Genome Science |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 |
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指定閱讀 |
I. Craig NL, Cohen-Fix O, Green R, Greider CW, Storz G, Wolberger C (2010) Molecular Biology: Principles of Genome Fuction. Oxford Publisher
II. Lewin B (2010) “GENES X”, Jones and Bartlett Publisher. |
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參考書目 |
I. Watson JD, Baker TA, Bell SP, Gann A, Levin M, and Losick R. (2008) Molecular Biology of the Gene 6th edition. Cold Spring Harbor Laboratory Press.
II. Allison LA “Fundamental Molecular Biology”Blackwell Publishing. 2007 III. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Peter Walter. (2009) Molecular Biology of the Cell 5th edition. Garland Science.
注意：NCBI 已免費提供第四版 (4th edition) 下載服務 (http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4); 第五版已於 2009 年出版，不過還未上線。
IV. 世界第一簡單分子生物學 (作者：武村政春; 譯者：連程翔; 出版社：世茂; 審訂：張俊哲)
本書為深入淺出，提供分生基本全貌之絕佳書籍！
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
2-20 |
Introduction to Molecular Genetics |
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第2週 |
2-27 |
調整放假，放假一天 |
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第3週 |
3-05 |
The structure and function of chromosome |
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第4週 |
3-12 |
DNA replication |
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第5週 |
3-19 |
Types of DNA damage |
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第6週 |
3-26 |
Midterm I |
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第7週 |
4-02 |
Transcription in prokaryotes |
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第8週 |
4-09 |
Transcription in eukaryotes |
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第9週 |
4-16 |
RNA processing |
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第10週 |
4-23 |
The mechanism of translation |
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第11週 |
4-30 |
Gene regulation in development |
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第12週 |
5-07 |
Midterm II |
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第13週 |
5-14 |
Repair of DNA double-strand breaks and homologous recombination |
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第14週 |
5-21 |
Mobile DNA |
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第15週 |
5-28 |
Tools and Techniques in Molecular Genetics (I) |
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第16週 |
6-04 |
Tools and Techniques in Molecular Genetics (II) |
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第17週 |
6-11 |
Genome and Genetic Variation |
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第18週 |
6-18 |
Final |
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第2-1週 |
3-03 |
The structure and function of DNA |
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